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The urinary bladder , or simply bladder , is a hollow muscular organ in humans and other vertebrates that stores urine from the kidneys before disposal by urination. In the human the bladder is a hollow muscular, and distensible organ that sits on the pelvic floor. Urine enters the bladder via the ureters and exits via the urethra. The typical human bladder will hold between 300 and 500 ml (10.14 and 16.91 fl oz ) before the urge to empty occurs, but can hold considerably more. The Latin phrase for "urinary bladder" is vesica urinaria , and the term vesical or prefix vesico - appear in connection with associated structures such as vesical veins. The modern Latin word for "bladder" – cystis – appears in associated terms such as cystitis (inflammation of the bladder).

In humans, the bladder is a hollow muscular organ situated at the base of the pelvis. In gross anatomy, the bladder can be divided into a broad fundus, a body, an apex, and a neck. The apex is directed forward toward the upper part of the pubic symphysis, and from there the median umbilical ligament continues upward on the back of the anterior abdominal wall to the umbilicus. The peritoneum is carried by it from the apex on to the abdominal wall to form the middle umbilical fold. The neck of the bladder is the area at the base of the trigone that surrounds the internal urethral orifice that leads to the urethra. In males the neck of the urinary bladder is next to the prostate gland. The bladder has three openings. The two ureters enter the bladder at ureteric orifices, and the urethra enters at the trigone of the bladder. These ureteric openings have mucosal flaps in front of them that act as valves in preventing the backflow of urine into the ureters, known as vesicoureteral reflux. B...

Urine, excreted by the kidneys, collects in the bladder because of drainage from two ureters, before disposal by urination (micturition). Urine leaves the bladder via the urethra, a single muscular tube ending in an opening called the urinary meatus, where it exits the body. Urination involves coordinated muscle changes involving a reflex based in the spine, with higher inputs from the brain. During urination, the detrusor muscle contracts, and the external urinary sphincter and muscles of the perineum relax, allowing urine to pass through the urethra and out of the body. The urge to pass urine stems from stretch receptors that activate when between 300 - 400 mL urine is held within the bladder. As urine accumulates, the rugae flatten and the wall of the bladder thins as it stretches, allowing the bladder to store larger amounts of urine without a significant rise in internal pressure. Urination is controlled by the pontine micturition center in the brainstem. Stretch receptors in the ...

Inflammation and infection edit Cystitis refers to infection or inflammation of the bladder. It commonly occurs as part of a urinary tract infection. In adults, it is more common in women than men, owing to a shorter urethra. It is common in males during childhood, and in older men where an enlarged prostate may cause urinary retention. Other risk factors include other causes of blockage or narrowing, such as prostate cancer or the presence of vesico-ureteric reflux; the presence of outside structures in the urinary tract, such as urinary catheters; and neurologic problems that make passing urine difficult. Infections that involve the bladder can cause pain in the lower abdomen (above the pubic symphysis, so called "suprapubic" pain), particularly before and after passing urine, and a desire to pass urine frequently and with little warning (urinary urgency). Infections are usually due to bacteria, of which the most common is E coli. When a urinary tract infection or cystitis ...

Mammals edit All mammals have a urinary bladder. This structure begins as an embryonic cloaca. In the vast majority, this eventually becomes differentiated into a dorsal part connected to the intestine and a ventral part which becomes associated with the urinogenital passage and urinary bladder. The only mammals in which this does not take place are the platypus and the spiny anteater both of which retain the cloaca into adulthood. The mammalian bladder is an organ that regularly stores a hyperosmotic concentration of urine. It therefore is relatively impermeable and has multiple epithelial layers. The urinary bladder of the cetaceans (whales and dolphins) is proportionally smaller than that of land-dwelling mammals. Reptiles edit In all reptiles, the urinogenital ducts and the anus both empty into an organ called a cloaca. In some reptiles, a midventral wall in the cloaca may open into a urinary bladder, but not all. It is present in all turtles and tortoises as well as most lizar...